If you go on to the cdc website and look up attic rodent infestations they recommend removing soiled insulation.
Mice droppings in attic insulation.
In many cases a full attic restoration is required.
Because your attic likely has insulation that material can provide special issues when cleaning up following a rodent infestation.
Inspect your attic for tunnelling especially if your house has blown in insulation.
This waste is unhygenic can possibly spread disease and encourages new mice to enter.
The product can be sprayed or applied by a fogging machine which would kill any bacteria which may be present.
If insulation has been contaminated by rat droppings or urine the only cleanup option may be to remove the contaminated areas and properly dispose of it.
Mice scatter their droppings wherever they go making it impossible to perform spot clean ups.
Mice often tunnel in materials like this and can even get behind fiberglass insulation in order to keep them warm while they are nesting.
Mouse feces in the attic photographs how to clean of course mice always deficate and urinate in the attic.
Mix a biocide solution whether commercial or bleach water at the ratio of 10 parts water to one part household bleach.
Mice are fearful so if they can hide their whereabouts they will do so especially when they hear you coming.
When mice live in your attic they poop in your attic.